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Bristol-Myers Squibb and AstraZeneca do not review the information on this Web site and/or database for content, accuracy, or completeness. Use of and access to this information is subject to the terms, limitations, and conditions set by the Web site and/or database producer.

Bristol-Myers Squibb and AstraZeneca make no representation as to the accuracy or any other aspect of the information contained on such Web site and/or database, nor does Bristol-Myers Squibb or AstraZeneca necessarily endorse such Web site and/or database.

Low Blood Sugar

Monitoring Your Blood Sugar

Maintaining a normal blood sugar is an important goal. If you have type 2 diabetes, your high blood sugar may be controlled with the help of diet, exercise, and prescription medicines like Onglyza, when your doctor decides medicine is necessary. However, low blood sugar can happen even when you're doing everything you can to properly manage your type 2 diabetes. Ask your doctor how often you should check your blood sugar levels and what they should be, so you can treat low blood sugar quickly.

Type 2 Diabetes Treatment and Low Blood Sugar

Some type 2 diabetes medicines may put you at risk for low blood sugar. Onglyza is unlikely to cause your blood sugar to be lowered to a dangerous level (hypoglycemia) because it does not work well when your blood sugar is low; however low blood sugar may occur, particulary when Onglyza is taken with another diabetes medicine, such as a sulfonylurea or insulin. Tell your doctor if you take other diabetes medicines. A lower dose of that medicine may be required to reduce the risk of low blood sugar. If you have symptoms of low blood sugar, you should check your blood sugar and treat if low, then call your doctor.

Before you take Onglyza, tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Know the medicines you take. Keep a list of your medicines and show it to your doctor and pharmacist when you get a new medicine.

Low Blood Sugar Symptoms

Since you can't always prevent low blood sugar from happening, it's important to monitor your blood sugar levels and know the symptoms so you can treat it quickly. Symptoms of low blood sugar include:

  • Shaking
  • Hunger
  • Sweating
  • Headache
  • Rapid heartbeat
  • Change in mood
  • Change in vision


If you have symptoms of low blood sugar, you should check your blood sugar and treat if low, then call your doctor.

Learn more about your blood sugar numbers and how Onglyza works to help control high blood sugar in adults with type 2 diabetes.

Onglyza gives you extra help to treat high blood sugar

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IMPORTANT SAFETY INFORMATION for ONGLYZA (saxagliptin)

Do not take ONGLYZA if you are allergic to any of its ingredients. Serious allergic reactions can occur with ONGLYZA and may include swelling of the face, lips or throat, difficulty swallowing or breathing, swelling of the skin, hives, rash, itching, flaking, or peeling. If you have these symptoms, stop taking ONGLYZA and contact your doctor right away.

Serious side effects can happen to people taking ONGLYZA, including inflammation of the pancreas (pancreatitis) which may be severe and lead to death. Before taking ONGLYZA, tell your doctor if you ever had pancreatitis, gallstones, history of alcoholism, or high triglyceride levels. Stop taking ONGLYZA and contact your doctor right away if you have pain in your stomach area (abdomen) that is severe and will not go away. The pain may be felt going from your abdomen through to your back. The pain may happen with or without vomiting. These may be symptoms of pancreatitis.

When ONGLYZA is used with certain other diabetes medicines to treat high blood sugar, such as a sulfonylurea or insulin, the risk of low blood sugar (hypoglycemia) is higher. Symptoms of low blood sugar include shaking, hunger, sweating, headache, rapid heartbeat, change in mood, and change in vision. Follow your doctor’s instructions for treating low blood sugar.

When ONGLYZA is used with a thiazolidinedione (TZD), such as pioglitazone or rosiglitazone, to treat high blood sugar, peripheral edema (fluid retention) may become worse. If you have symptoms of peripheral edema, such as swelling of hands, feet, or ankles, call your doctor.

The most common side effects with ONGLYZA include upper respiratory tract infection, urinary tract infection, and headache.

Your doctor should test your blood to measure how well your kidneys are working before and during treatment with ONGLYZA. You may need a lower dose if your kidneys are not working well.

Tell your doctor if you start or stop taking other medications, including antibiotics, antifungals or HIV/AIDS medications, as your doctor may need to change your dose of ONGLYZA.

Tell your doctor if you are pregnant, breast-feeding, or plan to become pregnant or breast-feed.